How it works & sources

Where the dosing values come from, how the arithmetic runs, and — just as importantly — where this app rounds, estimates, assumes, or has no citation yet.

Dosing references

Every drug in the catalog names its dosing reference, and that reference is shown where the number appears rather than in a footnote. Across 152 dose regimens on 127 drugs:

SourceRegimens
BNFc47
IDAI41
BNF14
Fornas8
WHO6
Kemenkes4
BNF / label produk4
AHA PALS & ACLS 20203
BNF / BNFc3
Label produk / Lexicomp2
Label produk (Novalgin)2
Label produk (Unasyn)2
BNF / Walls Manual2
BNFc / Cochrane (Khemani 2009)1
IDAI (Rekomendasi Penatalaksanaan Kejang Demam 2016)1
AES 2016 / ESETT 20191
AES 2016 / IDAI1
IDAI / AES 20161
ESETT 2019 / AES 20161
BNF / Brain Trauma Foundation 20161
EMA 2013 / BNFc1
EMA 2013 / BNF1
Walls Manual of Emergency Airway Management / BNFc1
Walls Manual of Emergency Airway Management1
BNFc / Walls Manual1
BNF / BNFc; CRASH-21
Kemenkes (Pelayanan Kesehatan Neonatal Esensial)1

How a dose is calculated

  1. 1. Daily dose

    Body weight (kg) × dose (mg/kg/day) = total daily dose.

    The catalog always stores doses as mg/kg/day. The “per dose” mode changes how the number is displayed, not the size of the dose.

  2. 2. Maximum

    If the daily dose exceeds the drug’s ceiling it is capped there and flagged.

    133 of 152 dose regimens carry a daily or single-dose maximum. The app also computes the weight at which that ceiling starts binding, because above it the dose stops following body weight.

  3. 3. Dose per administration

    Daily dose ÷ frequency = the amount given each time.

  4. 4. Volume

    Dose per administration ÷ stock concentration (mg/mL) = volume in mL.

    Concentration depends on the preparation in your hand, so the catalog stores it for only 82 regimens; you supply the rest.

  5. 5. Real preparations

    The per-dose amount is translated into what exists: ¼, ½, ¾, 1, 1½ tablets, or a syrup volume.

    Because tablets only split at certain fractions, the app shows the dose actually delivered and how far it is from the calculated figure.

Known limitations

Every calculator makes assumptions. These are the ones DoseRx makes.

Rounding of solid forms

Tablets are rounded to splittable fractions, so the delivered dose can land slightly above or below the calculated one. The gap is always shown; liquids are measured continuously and are not rounded.

Weight estimated from age

Uses APLS (0–12 months and 1–10 years) and Luscombe & Owens (>10 years). These are population averages that ignore nutritional status — high for a wasted child, low for an obese one. Weigh the patient where possible.

Compounded powders (puyer)

The calculation assumes the powder mixes evenly and divides equally across sachets. Per-sachet accuracy depends on the compounding itself.

Infusions

Drops per minute assume a giving set of 20 drops/mL (macro) or 60 drops/mL (micro); yours may differ. Each drug's default concentration assumes a specific dilution, which is stated next to the field. 7 of 12 drips do not yet cite a source — an acknowledged gap.

Scope

DoseRx is

  • a weight-based dose calculation aid
  • a dosing reference catalog with its sources named
  • a personal tool that runs entirely on your device

DoseRx is not

  • a clinical decision support system
  • a prescribing or prescription-printing system
  • a drug interaction checker
  • a complete pharmacy database
  • a regulator-certified product

Data & privacy

  • No server. Every calculation runs in your browser.
  • History, custom presets and favourites live in this device’s localStorage only.
  • No analytics, no trackers, no third-party requests — including the font.
  • Patient labels are optional; use initials only, never full names.

DoseRx is a calculation aid, not a clinical decision support or prescribing system. Preset dosing values are general references and do not replace clinical judgement. Verify every dose against institutional guidance and current clinical sources before use.

How new entries are reviewed

New drugs and routes are added as drafts with a cited source, and stay hidden until a clinician has checked them. Open the review list