Tag
#genetics
5 articles
CRISPR: Programmable Molecular Scissors
How CRISPR-Cas9 uses a guide RNA to find and cut a matching DNA sequence, why the cell's own repair machinery makes the actual edit, and where the risks and hype diverge.
Natural Selection
How three plain requirements — variation, heritability, and differential reproduction — force populations to change, why the algebra of allele frequencies makes it inevitable, and where random drift takes over from selection.
Heredity and Mendelian Genetics
How Mendel's pea experiments overturned blending inheritance, why a monohybrid cross gives 3:1 and a dihybrid 9:3:3:1, and how the Punnett square is just a probability calculation over discrete alleles.
From DNA to Protein
The central dogma as information flow: transcription into messenger RNA, the triplet code and its built-in redundancy, translation at the ribosome, and why one genome can build hundreds of different cells.
DNA Replication
The replication fork, the antiparallel problem that forces one strand to be built backwards in pieces, and the layered error correction that drives the final error rate down to one in a billion.